Surgeon general wants more people to carry opioid overdose-reversing drug

U.S. Surgeon General Jerome Adams, in April, urged more Americans to carry a lifesaving medication that can reverse the effects of an opioid overdose.

The medication, naloxone (sold under the trade name Narcan), is already carried by many first responders, such as EMTs and police officers. The surgeon general recommends that more individuals, including family, friends and those who are personally at risk for an opioid overdose, also keep the drug on hand.

An estimated 2.1 million people in the U.S. struggle with an opioid use disorder, according to data from the Centers for Disease Control and Prevention. Rates of opioid overdose deaths are rapidly increasing. Since 2010, the number of opioid overdose deaths has doubled from more than 21,000 to more than 42,000 in 2016, with the sharpest increase occurring among deaths related to illicitly made fentanyl and fentanyl analogs, or synthetic opioids.

Opioids are a class of drugs that include medications such as oxycodone, hydrocodone and methadone, which are commonly prescribed to treat pain. Pharmaceutical fentanyl is a synthetic opioid which is 50 times more potent than heroin and 100 times more potent than morphine. It is approved for treating severe pain, typically post-surgical or advanced cancer pain. However, most recent cases of fentanyl-related health problems are a result of illicitly made fentanyl.

“It is time to make sure more people have access to this lifesaving medication,” Adams said, “because 77 percent of opioid overdose deaths occur outside of a medical setting and more than half occur at home.”

Naloxone, an FDA-approved medication that can be delivered via nasal mist or injection, is not a long-term solution, but it can temporarily suspend the effects of the overdose until emergency responders arrive.

“To manage opioid addiction and prevent future overdoses, increased naloxone availability must occur in conjunction with expanded access to evidence-based treatment for opioid use disorder,” Adams said.

All states have passed laws to increase access to naloxone and you can walk into a pharmacy and request naloxone even if you don’t already have a prescription. In addition, most states have laws designed to protect health care professionals for prescribing and dispensing naloxone from civil and criminal liabilities as well as Good Samaritan laws to protect people who administer naloxone or call for help during an opioid overdose emergency.

Naloxone is covered by most insurance plans and, for those without coverage, may be available at low or no cost through local public health programs or through retailer and manufacturer discounts. It is easy to use, safe to administer and widely available.

The surgeon general’s report on naloxone is part of the administration’s ongoing effort to respond to the sharp increase among drug overdose deaths. Just last month, the Centers for Disease Control and Prevention released new data showing a rise in emergency department visits for opioid overdoses. From July 2016 through September 2017, opioid overdoses increased 30 percent in all parts of the U.S.

Expanding the use of the overdose-reversing drug naloxone is a key part of the public health response to the opioid crisis, along with effective prevention, treatment and recovery programs for opioid use disorder. Research shows a combination of medication, counseling and behavioral therapy, also known as Medication Assisted Treatment, or MAT, can help people achieve long-term recovery.

A Kansas pharmacist who asked not to be identified said naloxone needs to be purchased with care.

“I don’t know any addicts. Every place is different. I watch very carefully what prescriptions go to who, and we in Kansas have K-TRACS, which allows pharmacists to track a person’s drug purchases from any pharmacy in the state and it’s getting tied into other state systems, as well,” the pharmacist said.

“As someone who isn’t, say, a first responder, I wouldn’t buy it. I wouldn’t have a need. But, if I knew someone and suspected they had an opioid problem, though, that’s when I’d buy it. It’s pricey at a cash price of $260 a dose here, but there are a lot of discounts out there for first responders and others who need access to Narcan.”

The pharmacist then mentioned a recent Kansas Department of Health and Environment statistic showing Kansas pharmacists reduced their sales of opioids by nearly 9 percent in 2017 compared with 2016.

“Between the doctors and pharmacists, we are cutting down on patient pill shopping. Not just here, but all over the country as the states start networking their tracking systems,” the pharmacist said. “If anything, I’d be more worried about the importation of illegal fentanyl coming in from Mexico and other points than I would be about prescription opioid abuse in Kansas.”

The pharmacist also said health care providers need to be better listeners to their patients, because what may be thought to be physical pain might be mental anguish instead.

“If anything, I think doctors and pharmacists need to be looking at being proactive at detecting depression and anxiety rather than pain, because in my travels as a pharmacist, I’ve seen places where I’ve dispensed more anti-depressants and fewer opioids and places where it’s more opioids than anti-depressants,” he said. “We maybe all need to be better at helping our patients at detecting what’s anxiety and depression rather than pain.”

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For more information on how to get help, call the Substance Abuse and Mental Health Service Administration’s National Helpline at 1-800-662-HELP (4357) or go to https://www.findtreatment.samhsa.gov to find a treatment center.

To learn more about how individuals can recognize and respond to an opioid overdose, visit www.surgeongeneral.gov to read more.

Larry Dreiling can be reached at 785-628-1117 or [email protected].